Yamamoto, M-T., Watanabe, M., Nagai, Y., Daicho, H., Ueda, M., Yamamoto, S., and N. Takemori
Drosophila Genetic Resource Center, Kyoto Institute of Technology
Saga Ippongi-cho, Ukyo-ku, Kyoto 616-8354, Japan

 Drosophila Proteome Atlas originally constructed by Matsumoto et al., (2007), and opened to the public at both University of Oklahoma and Drosophila Genetic Resource Center (DGRC), Kyoto Institute of Technology. The Drosophila protein database provides protein maps displayed on two-dimensional (2D) gel electrophoresis. Protein was identified by peptide mass fingerprinting followed by the confirmation by MS/MS. The 2D gel electrophoresis renders a map of proteins that exist in the sample of interest with rich information on proteome, including post-translational modification and the comparative quantities of expressed proteins. We are now extending proteome studies to the reproductive system in both males and females, and also in the course of fertilization (Takemori and Yamamoto, 2009). These new data sets will be uploaded and opened in turns from July 2009. We are pleased to release a new version of Drosophila Proteome Atlas with a new Altas Viewer, with which protein map and corresponding protein information can be viewed more easily and all proteins we analyzed are linked to FlyBase. The original sets of data previously announced on the brain and compound eyes will also be released with the new viewer. This database surely provide numerous information on Drosophila proteome dynamics when it comes to understanding biological functions of various proteins in the tissues and organs concerning the reproductive system in the process of gamete formation, maturation, storage, and fertilization. It is our hope that the 2D gel protein profiles and proteomics information will add a new phase to research projects, protein processing and RNAi transgenes, for example, and accelerate their progress.

Acknowledgements: This work was supported by a grant from Grants-in-Aid for Publication of Scientific Research Results to MTY.