2024
Nitta Y., Osaka J., Maki R., Hakeda-Suzuki S., Suzuki E., Ueki S., Suzuki T., Sugie A., (2024) eLife 10.7554/eLife.87880.2 model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy.
Chauvin SD, Ando S, Holley JA, Sugie A., Zhao FR, Poddar S, Kato R, Miner CA, Nitta Y, Krishnamurthy SR, Saito R, Ning Y, Hatano Y, Kitahara S, Koide S, Stinson WA, Fu J, Surve N, Kumble L, Qian W, Polishchuk O, Andhey PS, Chiang C, Liu G, Colombeau L, Rodriguez R, Manel N, Kakita A, Artyomov MN, Schultz DC, Coates PT, Roberson EDO, Belkaid Y, Greenberg RA, Cherry S, Gack MU, Hardy T, Onodera O, Kato T,corresponding author and Miner JJ,corresponding author. (2024) Nat Commun. 15: 4696. Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans.
Iida T., Igarashi A., Fukunaga K., Aoki T., Hidai T., Yanagi K., Yamamori M., Satou K., Go H., Kosho T., Maki R., Suzuki T., Nitta Y., Sugie A., Asaoka Y., Furutani-Seiki M., Kimura T., Matsubara Y., Kaname T. (2024) Front. Genet. 15:1383176. doi: 10.3389/fgene.2024.1383176 Functional analysis of RRAS2 pathogenic variants with a Noonan-like phenotype.
Osaka J, Ishii A, Wang X, Iwanaga R, Kawamura H, Akino S, Sugie A, Hakeda-Suzuki S, Suzuki T. (2024) Cell Rep. Feb 19;43(2):113798. doi: 10.1016/j.celrep.2024.113798. Online ahead of print. PMID: 38381608 Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity.
2023
Vetro et al., (2023) The American Journal of Human Genetics 110(8):1356-1376. doi: 10.1016/j.ajhg.2023.06.008 Stretch-activated ion channel TMEM63B associates with developmental and epileptic encephalopathies and progressive neurodegeneration.
Yamada M., Nitta Y. Uehara T., Suzuki H., Takenouchi T., Tamura M., Ayabe S., Yoshiki A., Maeno A., Saga Y., Tamio Furuse T., Yamada I., Okamoto N., Sugie A.†, Kosaki K.†, (2023) European Journal of Medical Genetics 66(8):104804. doi: 10.1016/j.ejmg.2023.104804 Heterozygous loss-of-function DHX9 variants are associated with neurodevelopmental disorders.† Co-corresponding authors
Nitta Y., Osaka J., Maki R., Hakeda-Suzuki S., Suzuki E., Ueki S., Suzuki T., Sugie A., (2023) eLife Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy. reviewed preprint
Itai T., Sugie A., Nitta Y., Maki R., Suzuki T., Shinkai Y., Watanabe Y., Nakano Y., Ichikawa K., Okamoto N., Utsuno Y., Koshimizu E., Fujita A., Hamanaka K., Uchiyama Y., Tsuchida N., Miyake N., Misawa K., Mizuguchi T., Miyatake S., Matsumoto N. (2023) Scientific Reports, Volume 13, Article number: 975. A novel NONO variant that causes developmental delay and cardiac phenotypes.
Nitta Y., Kawai H., Maki R., Osaka J., Hakeda-Suzuki S., Nagai Y., Doubková K., Uehara T., Watanabe K., Kosaki K., Suzuki T., Tavosanis G., Sugie A. (2023) Human Molecular Genetics, Volume 32, Issue 9, Pages 1524-1528. Direct evaluation of neuroaxonal degeneration with the causative genes of neurodegenerative diseases in Drosophila using the automated axon quantification system, MeDUsA. SugieLab/MeDUsA (github.com)
2022
Osaka J., Yasuda H., Watanuki Y., Kato Y., Nitta Y., Sugie A., Sato M., Suzuki T. (2022) Genes & Genetic Systems, Volume 97, Issue 6, Pages 297-309. Identification of genes regulating stimulus-dependent synaptic assembly in Drosophila using an automated synapse quantification system.
Nitta Y., Sugie A.. (2022) Fly, Volume 16, Issue 1, Pages 275-298. Studies of neurodegenerative diseases using Drosophila and the development of novel approaches for their analysis.
Richard M., Doubková K., Nitta Y., Kawai H., Sugie A.†, Tavosanis G.† (2022) The Journal of Neuroscience, Volume 42, Issue 24, Pages 4937-4952. A Quantitative Model of Sporadic Axonal Degeneration in the Drosophila Visual System.† Co-corresponding authors
Utomo Y. R., Sugie A.†, Okada S., Miura K., Nakamura H.† (2022) Chemical Communications, Volume 58, Issue 15, Pages 2576-2579. Detoxification of amyloid β fibrils by curcumin derivatives and their verification in a Drosophila Alzheimer’s model. † Co-corresponding authors
2021
Kato T., Manabe R., Igarashi H., Kametani F., Hirokawa S., Sekine Y., Fujita N., Saito S., Kawashima Y., Hatano Y., Ando S., Nozaki H., Sugai A., Uemura M., Fukunaga M., Sato T., Koyama A., Saito R., Sugie A., Toyoshima Y., Kawata H., Murayama S., Matsumoto M., Kakita A., Hasegawa M., Ihara M., Kanazawa M., Nishizawa M., Tsuji S., Onodera O. (2021) Journal of Clinical Investigation, Volume 131, Issue 22, e140555. Candesartan prevents arteriopathy progression in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy model.
Sakamoto M., Sasaki K., Sugie A., Nitta Y., Kimura T., Gürsoy S., Cinleti T., Iai M., Sengoku T., Ogata K., Suzuki A, Okamoto N., Iwama K., Tsuchida N., Uchiyama Y., Koshimizu E., Fujita A., Hamanaka K., Miyatake S., Mizuguchi T., Taguri M., Ito S., Takahashi H., Miyake N., Matsumoto N. (2021) Human Molecular Genetics, Volume 31, Issue 1, Pages 69-81. De novo ARF3 variants cause neurodevelopmental disorder with brain abnormality
Takechi H., Hakeda-Suzuki S., Nitta Y., Ishiwata Y., Iwanaga R., Sato M., Sugie A., Suzuki T. (2021) eLife, Volume 10, e66718. Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon guidance.
2019
Nitta Y., Matsui S., Kato Y., Kaga Y., Sugimoto K., Sugie A. (2019) Scientific Reports, Volume 9, Article number: 8857. Analysing the evolutional and functional differentiation of four types of Daphnia magna cryptochrome in Drosophila circadian clock.
2018
Sugie A., Marchetti G., Tavosanis G. (2018) Neural Development, Volume 13, Article number: 14. Structural aspects of plasticity in the nervous system of Drosophila.
Itoh, M., Kajihara, R., Kato, Y., Takano-Shimizu, T., and Inoue, Y. (2018) Frequencies of chromosomal inversions in Drosophila melanogaster in Fukushima after the nuclear power plant accident. PLoS ONE 13(2): e0192096
植田充美 監修／高野敏行他36名 バイオテクノロジーシリーズ – AI導入によるバイオテクノロジーの発展 Development of Biotechnology by the Introduction of AI シーエムシー出版 2018年2月9日発行
Tomaru, M., Ohsako, T., Watanabe, M., Juni, N., Matsubayashi, H., Sato, H., Takahashi, A., & Yamamoto, M.-T. 2018. Severe fertility effects of sheepish sperm caused by failure to enter female sperm storage organs in Drosophila melanogaster. G3 (Bethesda) 8: 149–160 https://doi.org/10.1534/g3.117.300171
2017
Sugie A.†, Möhl C.†, Hakeda-Suzuki S., Matsui H., Suzuki T., Tavosanis G. (2017) Journal of Visualized Experiments, 120, e55716. Analyzing synaptic modulation of Drosophila photoreceptors after exposure to prolonged light. † Co-corresponding authors
Nitta Y.† and Sugie A.† (2017) Biochemical and Biophysical Research Communications, Volume 487, Issue 1, Pages 116-121. DISCO Interacting Protein 2 determines direction of axon projection under the regulation of c-Jun N-terminal kinase in the Drosophila mushroom body. † Co-corresponding authors
Nitta Y.† and Sugie A.† (2017) Biochemical and Biophysical Research Communications, Volume 487, Issue 4, Pages 898-902. Identification of glaikit in a genome-wide expression profiling for axonal bifurcation of the mushroom body in Drosophila. † Co-corresponding authors
Nitta Y., Yamazaki D., Sugie A., Hiroi M., Tabata T. (2017) Developmental Biology, Volume 421, Issue 2, Pages 233-244. DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons.
Matsumoto, Y., Goto, T., Nishino, J., Nakaoka, H., Tanave, A., Takano-Shimizu, T., Mott, R. F., and Koide, T. (2017) Selective breeding and selection mapping using a novel wild-derived heterogeneous stock of mice revealed two closely-linked loci for tameness. Scientific Reports 7, 4607
鷲谷いづみ 監修／桂勲 編 高野敏行他7名 遺伝学 –遺伝子から見た生物– 培風館 2017年1月20日発行
2015
Sugie A., Hakeda-Suzuki S., Suzuki E., Silies M., Shimozono M., Möhl C., Suzuki T. and Tavosanis G. (2015) Neuron, Volume 86, Issue 3, Pages 711-725. Molecular remodeling of the presynaptic active zone of Drosophila photoreceptors via activity-dependent feedback.
2014
Kanamori, T., Yasuno, Y., Tomaru, T., and Takano-Shimizu-Kouno, T. Reduced male fertility of the Canton-S strain due to spermiogenic failure. (2014) Drosophila Information Service 97, 21-24
遺伝子が語る生命38億年の謎 － なぜ、ゾウはネズミより長生きか？、2014年6月、悠書館（国立遺伝学研究所 編 第1章を執筆）
Tanaka,K.M.*,Takahashi,A.,Fuse,N.,and Takano-Shimizu-Kouno,T.* （2014）A novel cell death gene acts to repair patterning defects in Drosohila melanogaster.Genetics 197,739-742. doi:10.1534/genetics.114.163337.Text Shirata, M., Araye, Q., Maehara, K., Enya, S., Takano-Shimizu, T., and Sawamura, K. (2014) Allelic asymmetry of the Lethal hybrid rescue (Lhr) gene expression in the hybrid between Drosophila melanogaster and D. simulans: confirmation by using genetic variations of D. melanogaster. Genetica 142, 43-48.Text
2013
Berger-Müller S.†, Sugie A.†, Takahashi F., Tavosanis G., Hakeda-Suzuki S., Suzuki T. (2013) PLOS ONE, Volume 8, Issue 12, e83732. Assessing the role of cell-surface molecules in central synaptogenesis in the Drosophila visual system.
†These authors contributed equally.
遺伝子図鑑、2013年10月、悠書館（国立遺伝学研究所「遺伝子図鑑」編集委員会、斉藤成也、荒木弘之、角谷徹仁、小林武彦、高野敏行 編集）
岩波 生物学辞典 第5版、2013年2月、岩波書店（新項目「量的形質遺伝子座」の執筆と50項目の校閲を担当）
2012
Koide, T., Goto, T., and Takano-Shimizu T. (2012) Genomic Mixing to Elucidate the Genetic System of Complex Traits. Experimental Animals 61, 503-509.
Nishimura, A., Ishida, Y., Takahashi, A., Okamoto, H., Sakabe, M., Itoh, M., Takano-Shimizu, T., and Ozaki M. (2012) Starvation-induced elevation of taste responsiveness and expression of a sugar taste receptor gene in Drosophila melanogaster. Journal of Neurogenetics 26, 206-215.
進化学事典、2012年4月、日本進化学会編、共立出版（16.1「遺伝子とは」と20.21「形質の遺伝的変異」を担当）
Takahashi, A., Fujiwara-Tsujii, N., Yamaoka, R., Itoh, M., Ozaki, M. and Takano-Shimizu, T. (2012) Cuticular hydrocarbon content that affects male mate preference of Drosophila melanogaster from West Africa. Int. J. Evol. Biol. Volume 2012, Article ID 278903.
2011
Takahashi, A. and Takano-Shimizu, T. (2011) Divergent enhancer haplotype of ebony on inversion In(3R)Payne associated with pigmentation variation in a tropical population of Drosophila melanogaster. Molecular Ecol. 20, 4277-87.
Takahasi, K. R., Matsuo, T. and Takano-Shimizu-Kouno, T. (2011) Two types of cis-trans compensation in the evolution of transcriptional regulation. Proc. Natl. Acad. Sci. USA 108, 15276-15281
Takahashi, K. H., Daborn, P. J., Hoffmann, A. A., and Takano-Shimizu, T. (2011) Environmental stress-dependent effects of deletions encompassing Hsp70Ba on canalization and quantitative trait asymmetry in Drosophila melanogaster. PLoS ONE 6, e17295
2010
Sugie A., Umetsu D., Yasugi T., Fischbach K-F., Tabata T. (2010) Development, Volume 137, Issue 19, Pages 3303-3313. Recognition of pre- and postsynaptic neurons via nephrin/NEPH1 homologs is a basis for the formation of the Drosophila retinotopic map.
Yasugi T., Sugie A., Umetsu D., Tabata T. (2010) Development, Volume 137, Issue 19, Pages 3193-3203. Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe.
Taniue K., Nishida A., Hamada F., Sugie A., Oda T., Ui-Tei K., Tabata T., Akiyama T. (2010) Development, Volume 137, Issue 10, Pages 1755-1764. Sunspot, a link between Wingless signaling and endoreplication in Drosophila.
Itoh, M., Nanba, N., Hasegawa, M., Inomata, N., Kondo, R., Oshima, M. and Takano-Shimizu, T. (2010) Seasonal changes in the long-distance linkage disequilibrium in Drosophila melanogaster. J. Hered. 101, 26-32.
Sawamura, K., Maehara, K., Mashino, S., Kagesawa, T., Kajiwara, M., Matsuno, K., Takahashi, A., and Takano-Shimizu, T. (2010) Introgression of Drosophila simulans nuclear pore protein 160 in Drosophila melanogaster alone does not cause inviability but does cause female sterility Genetics 186, 669-676
Takahashi, K. H., Rako, L., Takano-Shimizu, T., Hoffmann, A.A., and Lee, S.F. (2010) Effects of small Hsp genes on developmental stability and microenvironmental canalization. BMC Evol. Biol. 10, 284
2009
Tatsuta, H. and Takano-Shimizu, T. (2009) High genetic differentiation between an African and a non-African strain of Drosophila simulans revealed by segregation distoration and reduced crossover frequency. Genetica 137, 165-171.
Fujikawa, K., Takahashi, A., Nishimura, A., Itoh, M., Takano-Shimizu, T. and Ozaki, M. (2009) Characteristics of genes up-regulated and down-regulated after 24 h starvation in the head of Drosophila. Gene 446, 11-17
Tanaka, K. M., Takahasi, K. R. and Takano-Shimizu, T. (2009) Enhanced fixation and preservation of a newly arisen duplicate gene by masking deleterious loss-of-function mutations. Genetics Research 91, 267-280.
Watanabe, Y., Takahashi, A., Itoh, M. and Takano-Shimizu, T. (2009) Molecular spectrum of spontaneous de novo mutations in male and female germline cells of Drosophila melanogaster. Genetics 181, 1035-1043.
Takahashi, K. H., Tanaka, K., Itoh, M. and Takano-Shimizu, T. (2009) Reduced X-linked rare polymorphism in males in comparison to females of Drosophila melanogaster. J. Heredity 100, 97-105.
進化 — 分子・個体・生態系、宮田隆、星山大介 監訳、メディカル・サイエンス・インターナショナル(第14章) p.413-445 (ISBN 4895926214) (“Evolution” (Barton, N. H., Briggs, D. E. G., Eisen, J. A., Goldstein, D. B., and Patel, N. H., 2007, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York), の第14章, “Variation in Genetically Complex Traits”, p. 381-412の日本語訳)
2008
Mizuno N., Sugie A., Kobayashi F., Takumi S. (2008) Journal of Plant Physiology, Urban & Fischer, Volume 165, Issue 4, Pages 462-467. Mitochondrial alternative pathway is associated with development of freezing tolerance in common wheat.
Inomata, N., Itoh, M., Kondo, R., Ohshima, M., Inoue, Y., and Takano-Shimizu, T. (2008). A new test for detecting ongoing selection. Genetica 133, 321-334
2007
Sugie A., Murai K., Takumi S. (2007) Genes and Genetic Systems, Genetics Society Of Japan, Volume 82, Issue 3, Pages 231-239. Alteration of respiration capacity and transcript accumulation level of alternative oxidase genes in necrosis lines of common wheat.
Takahashi, A., Takahashi, K., Ueda, R., and Takano-Shimizu, T. (2007). Natural variation of ebony gene controlling thoracic pigmentation in Drosophila melanogaster. Genetics 177, 1233-1237.
Noro,Y., Takano-Shimizu,T., Syono, K., Kishima,Y., and Sano, Y. (2007). Genetic variations in rice in vitro cultures at the EPSPs-RPS20 region. Theor. Appl. Genet. 114, 705-711. Text
2006
Sugie A., Naydenov N., Mizuno N., Nakamura C., Takumi S. (2006) Genes and Genetic Systems, Genetics Society Of Japan, Volume 81, Issue 5, Pages 349-354. Overexpression of wheat alternative oxidase gene Waox1a alters respiration capacity and response to reactive oxygen species under low temperature in transgenic Arabidopsis.
Tatsuta, H., and Takano-Shimizu, T. (2006). Genetic architecture of variation in sex-comb tooth number in Drosophila simulans. Genet. Res. 87, 93-107.
Takeuchi, T., Watanabe, Y., Takano-Shimizu , T., Kondo, S. (2006). Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev. Dyn. 235, 2449-2459.
2005
Kobayashi, S., Noro, Y., Nagano, H., Yoshida, K., Takano-Shimizu, T., Kishima, Y., and Sano, Y. (2005). Evidence for an evolutionary force that prevents epigenetic silencing between tail-to-tail rice genes with a short spacer. Gene 346, 231-240.
Takahashi, A., and Takano-Shimizu, T. (2005). A high frequency null mutant of an odorant-binding protein gene, Obp57e, in Drosophila melanogaster. Genetics 170, 709-18.
遺伝学事典、2005年、東江昭夫、徳永勝士、町田泰則 編、朝倉書店(ISBN 4254171242) (対立遺伝子、優性、不完全優性、表現型、交雑、雑種、雑種強勢、他家受精、両性雑種、モルガン単位、異型接合の11項目について執筆)
2004
Takano-Shimizu, T., Inomata, N., Nanba, N., Kondo, R., Inoue, Y., and Itoh, M. (2004). Inter-locus nonrandom association of polymorphisms in Drosophila chemoreceptor genes. Proc. Natl. Acad. Sci. USA 101, 14156-14161.
Oka, A., Mita, A., Sakurai-Yamatani, N., Yamamoto, H., Takagi, N., Takano-Shimizu, T., Toshimori, K., Moriwaki, K., and Shiroishi, T. (2004). Hybrid breakdown caused by substitution of the X chromosome between two mouse subspecies. Genetics 166, 913-924. Text
2002
Sakai, T., Isono, K., Tomaru, M., Fukatami, A., and Oguma, Y. (2002). Light wavelength dependency of mating activity in the Drosophila melanogaster species subgroup. Genes Genet. Sys. 77, 187 – 195.
Yamada, H., Sakai, T., Tomaru, M., Doi, M., Matsuda, M., and Oguma, Y. (2002). Search for species-specific mating signal in courtship songs of sympatric sibling species, Drosophila ananassae and D. pallidosa. Genes Genet. Sys. 77, 97 – 106.
Furuse, T., Takano-Shimizu, T., Moriwaki, K., Shiroishi, T., and Koide, T. (2002). QTL analyses of spontaneous activity by using mouse strains from Mishima battery. Mamm. Genome 13, 411-415.
2001
Takano-Shimizu, T. (2001). Local changes in GC/AT substitution biases and in crossover frequencies on Drosophila chromosomes. Mol. Biol. Evol.18, 606-619.
Doi, M., Matsuda, M., Tomaru, M., Matsubayashi, H., and Oguma, Y. (2001). A locus for female discrimination behavior causing sexual isolation in Drosophila. Proc. Natl. Acad. Sci. USA 98, 6714 – 6719.
2000
Takano-Shimizu, T. (2000). Genetic screens for factors involved in the notum bristle loss of interspecific hybrids between Drosophila melanogaster and D. simulans. Genetics 156, 269-282
Tomaru, M., and Oguma, Y. (2000) Mate choice in Drosophila melanogaster and D. sechellia: criteria and their variation depending on courtship song. Anim. Behav. 60, 797 – 804
Tomaru, M., Doi, M, Higuchi, H., and Oguma, Y. (2000) Courtship song recognition in the Drosophila melanogaster complex: Heterospecific songs makes females receptive in D. melanogaster but not in D. sechellia. Evolution 54, 1286 – 1294 .
1999
Takano-Shimizu, T. (1999). Local recombination and mutation effects on molecular evolution in Drosophila. Genetics 153, 1285-1296.
Yamashita, S., Takano-Shimizu, T., Kitamura, K., Mikami, T., and Kishima, Y. (1999). Resistance to gap repair of the transposon Tam3 in Antirrhinum majus: A role of the end regions. Genetics 153, 1899-1908. Text .
1998
Takano, T. S. (1998). Loss of notum macrochaetae as an inter-specific hybrid anomaly between Drosophila melanogaster and D. simulans. Genetics 149, 1435-1450.
Takano, T. S. (1998). Rate variation of DNA sequence evolution in the Drosophila lineages. Genetics 149, 959-970.
Tomaru, M., Matsubayashi, H., and Oguma, Y. (1998) Effects of courtship song in inter-specific crosses among the species of the Drosophila auraria complex (Diptera: Drosophilidae). J. Insect Behav. 11, 383 – 398.
