Drosophila Genomics and Genetic Resources

Date	:	Wednesday, October 7th, 2015
Time	:	16:10-17:10
Location	:	4-th floor Seminar room, University Laboratories for Innovative Research (Matsugasaki, Sakyo-ku, Kyoto)
Speaker	:	Dr. Maria Dulcetti Vibranovski Department of Genetics and Evolutionary Biology University of São Paulo
Title	:	"Spermatogenesis and the Evolutionary Reorganization of the Genome"
Abstract	:	Although more than a decade has passed since the first eukaryotic genome was sequenced, the molecular basis of genome organization and complexity remains a largely unresolved problem. The relationship of genotype to phenotype has proven particularly challenging. I use gametogenesis in Drosophila as a model system to study the evolution and phenotypic expression of genomic features. Gametogenesis is a fascinating biological process; it varies temporally throughout development, and has profound evolutionary impact in that it provides the raw material for the next generation - the gamete. To date, gametogenesis research has primarily focused on single gene studies of fertility. In contrast, I apply a genomic perspective to the overall process of gametogenesis to understand the role sexual selection plays in genome evolution. In my research on genome evolution in Drosophila melanogaster, I have combined bioinformatics and statistics with experimental genomic and molecular genetic methods to obtain large-scale gene expression data on gametogenesis, or spermatogenic-stage-specific transcriptome (SpermPress). The results help to solve two classical problems that have puzzled biologists for decades: evidence for Meiotic Sex Chromosome inactivation and for Post-meiotic transcription. In this talk, I present the results obtained through the application of advanced Bayesian statistics to Gene Chip microarray data. I also introduce another puzzle yet to be solved in the evolutionary biology field related to the role of sperm haploid selection in the evolution of new genes.

Chairperson

:

Tim Karr

For more infomation, contact: Takano, Toshiyuki
Dept. Drosophila Genomics and Genetic Resources
Tel. 075-873-2660
Please contact from this form.



このセミナーは平成27年度国際化モデル研究室に採択された「国際交流を起爆剤に推進する精子ゲノム学」事業の一環として実施するものです